| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.100 | GeneticVariation | disease | BEFREE | We could not properly analyze IL17A -692 C>T (rs8193036) and IFNG +874T>A due to genotypic inconsistencies and found no evidence of association for the IL2, IL4, IL10 and TNF polymorphisms and PTB. | 26840977 | 2016 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | This study compared the frequency of the genetic polymorphisms of tumor necrosis factor (TNF) in pulmonary tuberculosis without and with response to treatment. | 20180006 | 2010 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | Our results indicated that the variants in TNF-α gene were associated with susceptibility to PTB and clinical severity of disease, whereas no significance could be inferred from TLRs and IL-10 genes polymorphisms. | 20650298 | 2010 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | The aims of the current investigation were to determine whether functional polymorphisms in the tumor necrosis factor-alpha (TNF-alpha) gene at position -308; in the transforming growth factor-beta 1 (TGF-beta1) gene at positions -509, +869 (codon 10), and +915 (codon 25); in the interleukin-10 (IL-10) gene at position -1,082, -819 and -592; and in the intron 1 of the interferon-gamma (IFN-gamma) gene at position +874 are associated with silicosis and PTB. | 18931463 | 2008 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | Of the HLA-TNF haplotypes analysed, the infrequent allele (A) of TNFalpha238 was in strong linkage disequilibrium with HLA-A1 (P corrected: Pc=0.001), B17 (Pc<0.0001) and DR7 (Pc=0.01) in control subjects and with B17 (Pc<0.0001) in pulmonary tuberculosis. | 11800584 | 2001 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | : HLA, IFNG, TNF, NRPAM1, IL10) variants and the development of active pulmonary TB. | 27101784 | 2016 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | Collectively, our results showed that analysed SNPs in the TNF-α and IL-10 gene polymorphisms play key role in susceptibility to or protection against TB development in Tunisian populations. | 21609779 | 2011 |